NOTCH1-UHRF1BP1L Fusion FISH Probe
The NOTCH1-UHRF1BP1L Fusion FISH Probe is used to confirm a fusion of the NOTCH1 and UHRF1BP1L genes. The fusion of the NOTCH1 and UHRF1BP1L genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NOTCH1-UHRF1BP1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-RERE | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-REOR | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-REGO | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-REGR | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-REAQ | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-ORRE | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-OROR | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-ORGO | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-GORE | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-GOOR | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-GOGO | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-GOGR | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-GRRE | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-GROR | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-GRGO | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-GRGR | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-AQRE | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-AQOR | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-AQGO | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-AQGR | 20 (40 μL) | 200 μL |
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| NOTCH1-UHRF1BP1L-20-AQAQ | 20 (40 μL) | 200 μL |
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NOTCH1 Gene Summary
This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016]
Gene Name: Notch 1
Chromosome: CHR9: 139388895 -139440238
Locus: 9q34.3
UHRF1BP1L Gene Summary
The UHRF1 Binding Protein 1 Like (UHRF1BP1L) gene is located on chr12 :100430862-100536642 at 12q23.1.
Gene Name: UHRF1 Binding Protein 1 Like
Chromosome: CHR12: 100430862 -100536642
Locus: 12q23.1
Gene Diseases
The NOTCH1 UHRF1BP1L Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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