NOS2-MYO18A Fusion FISH Probe
The NOS2-MYO18A Fusion FISH Probe is used to confirm a fusion of the NOS2 and MYO18A genes. The fusion of the NOS2 and MYO18A genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NOS2-MYO18A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-RERE | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-REOR | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-REGO | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-REGR | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-REAQ | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-ORRE | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-OROR | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-ORGO | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-ORAQ | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-GORE | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-GOOR | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-GOGO | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-GOGR | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-GOAQ | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-GRRE | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-GROR | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-GRGO | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-GRGR | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-GRAQ | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-AQRE | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-AQOR | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-AQGO | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-AQGR | 20 (40 μL) | 200 μL |
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| NOS2-MYO18A-20-AQAQ | 20 (40 μL) | 200 μL |
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NOS2 Gene Summary
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Gene Name: Nitric Oxide Synthase 2
Chromosome: CHR17: 26083791 -26127555
Locus: 17q11.2
MYO18A Gene Summary
The protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016]
Gene Name: Myosin XVIIIA
Chromosome: CHR17: 27400527 -27507407
Locus: 17q11.2
Gene Diseases
The NOS2 MYO18A Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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