NOS1AP-DCAF6 Fusion FISH Probe
The NOS1AP-DCAF6 Fusion FISH Probe is used to confirm a fusion of the NOS1AP and DCAF6 genes. The fusion of the NOS1AP and DCAF6 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NOS1AP-DCAF6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-RERE | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-REOR | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-REGO | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-REGR | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-REAQ | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-ORRE | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-OROR | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-ORGO | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-ORAQ | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-GORE | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-GOOR | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-GOGO | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-GOGR | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-GOAQ | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-GRRE | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-GROR | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-GRGO | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-GRGR | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-GRAQ | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-AQRE | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-AQOR | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-AQGO | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-AQGR | 20 (40 μL) | 200 μL |
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| NOS1AP-DCAF6-20-AQAQ | 20 (40 μL) | 200 μL |
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NOS1AP Gene Summary
This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2009]
Gene Name: Nitric Oxide Synthase 1 Adaptor Protein
Chromosome: CHR1: 162039580 -162339813
Locus: 1q23.3
DCAF6 Gene Summary
The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression. [provided by RefSeq, Mar 2017]
Gene Name: DDB1 And CUL4 Associated Factor 6
Chromosome: CHR1: 167905796 -168045083
Locus: 1q24.2
Gene Diseases
The NOS1AP DCAF6 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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