NMT1-HIGD1B Fusion FISH Probe
The NMT1-HIGD1B Fusion FISH Probe is used to confirm a fusion of the NMT1 and HIGD1B genes. The fusion of the NMT1 and HIGD1B genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NMT1-HIGD1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-RERE | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-REOR | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-REGO | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-REGR | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-REAQ | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-ORRE | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-OROR | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-ORGO | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-GORE | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-GOOR | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-GOGO | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-GOGR | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-GRRE | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-GROR | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-GRGO | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-GRGR | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-AQRE | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-AQOR | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-AQGO | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-AQGR | 20 (40 μL) | 200 μL |
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| NMT1-HIGD1B-20-AQAQ | 20 (40 μL) | 200 μL |
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NMT1 Gene Summary
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008]
Gene Name: N-myristoyltransferase 1
Chromosome: CHR17: 43138679 -43186382
Locus: 17q21.31
HIGD1B Gene Summary
This gene encodes a member of the hypoxia inducible gene 1 (HIG1) domain family. The encoded protein is localized to the cell membrane and has been linked to tumorigenesis and the progression of pituitary adenomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Name: HIG1 Hypoxia Inducible Domain Family Member 1B
Chromosome: CHR17: 42925278 -42927848
Locus: 17q21.31
Gene Diseases
The NMT1 HIGD1B Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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