NME7-MKLN1 Fusion FISH Probe
The NME7-MKLN1 Fusion FISH Probe is used to confirm a fusion of the NME7 and MKLN1 genes. The fusion of the NME7 and MKLN1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NME7-MKLN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-RERE | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-REOR | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-REGO | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-REGR | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-REAQ | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-ORRE | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-OROR | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-ORGO | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-GORE | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-GOOR | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-GOGO | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-GOGR | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-GRRE | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-GROR | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-GRGO | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-GRGR | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-AQRE | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-AQOR | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-AQGO | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-AQGR | 20 (40 μL) | 200 μL |
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| NME7-MKLN1-20-AQAQ | 20 (40 μL) | 200 μL |
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MKLN1 Gene Summary
Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]
Gene Name: Muskelin 1
Chromosome: CHR7: 130794854 -131181398
Locus: 7q32.3
NME7 Gene Summary
This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Gene Name: NME/NM23 Family Member 7
Chromosome: CHR1: 169101768 -169337186
Locus: 1q24.2
Gene Diseases
The NME7 MKLN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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