NLRC5-NUP93 Fusion FISH Probe
The NLRC5-NUP93 Fusion FISH Probe is used to confirm a fusion of the NLRC5 and NUP93 genes. The fusion of the NLRC5 and NUP93 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NLRC5-NUP93-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-RERE | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-REOR | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-REGO | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-REGR | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-REAQ | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-ORRE | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-OROR | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-ORGO | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-ORAQ | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-GORE | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-GOOR | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-GOGO | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-GOGR | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-GOAQ | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-GRRE | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-GROR | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-GRGO | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-GRGR | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-GRAQ | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-AQRE | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-AQOR | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-AQGO | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-AQGR | 20 (40 μL) | 200 μL |
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| NLRC5-NUP93-20-AQAQ | 20 (40 μL) | 200 μL |
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NUP93 Gene Summary
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene encodes a nucleoporin protein that localizes both to the basket of the pore and to the nuclear entry of the central gated channel of the pore. The encoded protein is a target of caspase cysteine proteases that play a central role in programmed cell death by apoptosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Gene Name: Nucleoporin 93
Chromosome: CHR16: 56764016 -56878861
Locus: 16q13
NLRC5 Gene Summary
This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011]
Gene Name: NLR Family CARD Domain Containing 5
Chromosome: CHR16: 57023409 -57117436
Locus: 16q13
Gene Diseases
The NLRC5 NUP93 Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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