NLGN1-SEMA5B Fusion FISH Probe
The NLGN1-SEMA5B Fusion FISH Probe is used to confirm a fusion of the NLGN1 and SEMA5B genes. The fusion of the NLGN1 and SEMA5B genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NLGN1-SEMA5B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-RERE | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-REOR | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-REGO | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-REGR | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-REAQ | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-ORRE | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-OROR | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-ORGO | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-ORAQ | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-GORE | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-GOOR | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-GOGO | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-GOGR | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-GOAQ | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-GRRE | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-GROR | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-GRGO | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-GRGR | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-GRAQ | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-AQRE | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-AQOR | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-AQGO | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-AQGR | 20 (40 μL) | 200 μL |
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| NLGN1-SEMA5B-20-AQAQ | 20 (40 μL) | 200 μL |
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NLGN1 Gene Summary
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008]
Gene Name: Neuroligin 1
Chromosome: CHR3: 173116243 -174001116
Locus: 3q26.31
SEMA5B Gene Summary
This gene encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through which semaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. The protein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Semaphorin 5B
Chromosome: CHR3: 122628042 -122746576
Locus: 3q21.1
Gene Diseases
The NLGN1 SEMA5B Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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