SEARCH OUR PRODUCT CATALOG

NKAIN3-WRN Fusion FISH Probe

The NKAIN3-WRN Fusion FISH Probe is used to confirm a fusion of the NKAIN3 and WRN genes. The fusion of the NKAIN3 and WRN genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NKAIN3-WRN-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
NKAIN3-WRN-20-RERE 20 (40 μL) 200 μL
NKAIN3-WRN-20-REOR 20 (40 μL) 200 μL
NKAIN3-WRN-20-REGO 20 (40 μL) 200 μL
NKAIN3-WRN-20-REGR 20 (40 μL) 200 μL
NKAIN3-WRN-20-REAQ 20 (40 μL) 200 μL
NKAIN3-WRN-20-ORRE 20 (40 μL) 200 μL
NKAIN3-WRN-20-OROR 20 (40 μL) 200 μL
NKAIN3-WRN-20-ORGO 20 (40 μL) 200 μL
NKAIN3-WRN-20-ORAQ 20 (40 μL) 200 μL
NKAIN3-WRN-20-GORE 20 (40 μL) 200 μL
NKAIN3-WRN-20-GOOR 20 (40 μL) 200 μL
NKAIN3-WRN-20-GOGO 20 (40 μL) 200 μL
NKAIN3-WRN-20-GOGR 20 (40 μL) 200 μL
NKAIN3-WRN-20-GOAQ 20 (40 μL) 200 μL
NKAIN3-WRN-20-GRRE 20 (40 μL) 200 μL
NKAIN3-WRN-20-GROR 20 (40 μL) 200 μL
NKAIN3-WRN-20-GRGO 20 (40 μL) 200 μL
NKAIN3-WRN-20-GRGR 20 (40 μL) 200 μL
NKAIN3-WRN-20-GRAQ 20 (40 μL) 200 μL
NKAIN3-WRN-20-AQRE 20 (40 μL) 200 μL
NKAIN3-WRN-20-AQOR 20 (40 μL) 200 μL
NKAIN3-WRN-20-AQGO 20 (40 μL) 200 μL
NKAIN3-WRN-20-AQGR 20 (40 μL) 200 μL
NKAIN3-WRN-20-AQAQ 20 (40 μL) 200 μL

WRN Gene Summary

This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017]

Gene Name: Werner Syndrome RecQ Like Helicase

Chromosome: CHR8: 30890777 -31031277

Locus: 8p12

NKAIN3 Gene Summary

NKAIN3 is a member of a family of mammalian proteins (see NKAIN1; MIM 612871) with similarity to Drosophila Nkain (Gorokhova et al., 2007 [PubMed 17606467]).[supplied by OMIM, Jun 2009]

Gene Name: Sodium/potassium Transporting ATPase Interacting 3

Chromosome: CHR8: 63161500 -63903628

Locus: 8q12.3

Gene Diseases

The NKAIN3 WRN Fusion has been associated with the following diseases:

Disease Name
Uterine Carcinosarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.