NFXL1-COPS4 Fusion FISH Probe
The NFXL1-COPS4 Fusion FISH Probe is used to confirm a fusion of the NFXL1 and COPS4 genes. The fusion of the NFXL1 and COPS4 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NFXL1-COPS4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-RERE | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-REOR | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-REGO | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-REGR | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-REAQ | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-ORRE | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-OROR | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-ORGO | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-ORAQ | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-GORE | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-GOOR | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-GOGO | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-GOGR | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-GOAQ | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-GRRE | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-GROR | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-GRGO | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-GRGR | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-GRAQ | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-AQRE | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-AQOR | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-AQGO | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-AQGR | 20 (40 μL) | 200 μL |
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| NFXL1-COPS4-20-AQAQ | 20 (40 μL) | 200 μL |
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COPS4 Gene Summary
This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Name: COP9 Signalosome Subunit 4
Chromosome: CHR4: 83956238 -83996971
Locus: 4q21.22
NFXL1 Gene Summary
The Nuclear Transcription Factor, X-box Binding Like 1 (NFXL1) gene is located on chr4 :47849257-47916633 at 4p12.
Gene Name: Nuclear Transcription Factor, X-box Binding Like 1
Chromosome: CHR4: 47849257 -47916633
Locus: 4p12
Gene Diseases
The NFXL1 COPS4 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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