NFKBIZ-ZBED2 Fusion FISH Probe
The NFKBIZ-ZBED2 Fusion FISH Probe is used to confirm a fusion of the NFKBIZ and ZBED2 genes. The fusion of the NFKBIZ and ZBED2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NFKBIZ-ZBED2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-RERE | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-REOR | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-REGO | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-REGR | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-REAQ | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-ORRE | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-OROR | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-ORGO | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-ORAQ | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-GORE | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-GOOR | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-GOGO | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-GOGR | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-GOAQ | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-GRRE | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-GROR | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-GRGO | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-GRGR | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-GRAQ | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-AQRE | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-AQOR | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-AQGO | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-AQGR | 20 (40 μL) | 200 μL |
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| NFKBIZ-ZBED2-20-AQAQ | 20 (40 μL) | 200 μL |
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NFKBIZ Gene Summary
This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: NFKB Inhibitor Zeta
Chromosome: CHR3: 101546833 -101579869
Locus: 3q12.3
ZBED2 Gene Summary
The Zinc Finger BED-type Containing 2 (ZBED2) gene is located on chr3 :111311746-111314182 at 3q13.13.
Gene Name: Zinc Finger BED-type Containing 2
Chromosome: CHR3: 111311746 -111314182
Locus: 3q13.13
Gene Diseases
The NFKBIZ ZBED2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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