NFKBIE-SLC29A1 Fusion FISH Probe
The NFKBIE-SLC29A1 Fusion FISH Probe is used to confirm a fusion of the NFKBIE and SLC29A1 genes. The fusion of the NFKBIE and SLC29A1 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NFKBIE-SLC29A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-RERE | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-REOR | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-REGO | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-REGR | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-REAQ | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-ORRE | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-OROR | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-ORGO | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-GORE | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-GOOR | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-GOGO | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-GOGR | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-GRRE | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-GROR | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-GRGO | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-GRGR | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-AQRE | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-AQOR | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-AQGO | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-AQGR | 20 (40 μL) | 200 μL |
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| NFKBIE-SLC29A1-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC29A1 Gene Summary
This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Solute Carrier Family 29 Member 1 (Augustine Blood Group)
Chromosome: CHR6: 44187241 -44201888
Locus: 6p21.1
NFKBIE Gene Summary
The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011]
Gene Name: NFKB Inhibitor Epsilon
Chromosome: CHR6: 44225902 -44233525
Locus: 6p21.1
Gene Diseases
The NFKBIE SLC29A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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