NFIX-VDR Fusion FISH Probe
The NFIX-VDR Fusion FISH Probe is used to confirm a fusion of the NFIX and VDR genes. The fusion of the NFIX and VDR genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NFIX-VDR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-RERE | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-REOR | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-REGR | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-OROR | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-GROR | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| NFIX-VDR-20-AQAQ | 20 (40 μL) | 200 μL |
|
NFIX Gene Summary
The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters. The encoded protein can also stimulate adenovirus replication in vitro. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
Gene Name: Nuclear Factor I X
Chromosome: CHR19: 13106583 -13209610
Locus: 19p13.13
VDR Gene Summary
This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]
Gene Name: Vitamin D Receptor
Chromosome: CHR12: 48235319 -48298814
Locus: 12q13.11
Gene Diseases
The NFIX VDR Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|