NFIA-CDK2AP1 Fusion FISH Probe
The NFIA-CDK2AP1 Fusion FISH Probe is used to confirm a fusion of the NFIA and CDK2AP1 genes. The fusion of the NFIA and CDK2AP1 genes has been associated with Thymoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NFIA-CDK2AP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-RERE | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-REOR | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-REGO | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-REGR | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-REAQ | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-ORRE | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-OROR | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-ORGO | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-GORE | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-GOOR | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-GOGO | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-GOGR | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-GRRE | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-GROR | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-GRGO | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-GRGR | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-AQRE | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-AQOR | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-AQGO | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-AQGR | 20 (40 μL) | 200 μL |
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| NFIA-CDK2AP1-20-AQAQ | 20 (40 μL) | 200 μL |
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NFIA Gene Summary
This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Nuclear Factor I A
Chromosome: CHR1: 61542945 -61928460
Locus: 1p31.3
CDK2AP1 Gene Summary
The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
Gene Name: Cyclin Dependent Kinase 2 Associated Protein 1
Chromosome: CHR12: 123745539 -123756687
Locus: 12q24.31
Gene Diseases
The NFIA CDK2AP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Thymoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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