NFE2L2-AGPS Fusion FISH Probe
The NFE2L2-AGPS Fusion FISH Probe is used to confirm a fusion of the NFE2L2 and AGPS genes. The fusion of the NFE2L2 and AGPS genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NFE2L2-AGPS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-RERE | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-REOR | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-REGO | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-REGR | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-REAQ | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-ORRE | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-OROR | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-ORGO | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-ORAQ | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-GORE | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-GOOR | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-GOGO | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-GOGR | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-GOAQ | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-GRRE | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-GROR | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-GRGO | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-GRGR | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-GRAQ | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-AQRE | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-AQOR | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-AQGO | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-AQGR | 20 (40 μL) | 200 μL |
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| NFE2L2-AGPS-20-AQAQ | 20 (40 μL) | 200 μL |
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NFE2L2 Gene Summary
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015]
Gene Name: Nuclear Factor, Erythroid 2 Like 2
Chromosome: CHR2: 178095032 -178129859
Locus: 2q31.2
AGPS Gene Summary
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]
Gene Name: Alkylglycerone Phosphate Synthase
Chromosome: CHR2: 178257470 -178408564
Locus: 2q31.2
Gene Diseases
The NFE2L2 AGPS Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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