NFE2L1-NPEPPS Fusion FISH Probe
The NFE2L1-NPEPPS Fusion FISH Probe is used to confirm a fusion of the NFE2L1 and NPEPPS genes. The fusion of the NFE2L1 and NPEPPS genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NFE2L1-NPEPPS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-RERE | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-REOR | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-REGO | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-REGR | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-REAQ | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-ORRE | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-OROR | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-ORGO | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-ORAQ | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-GORE | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-GOOR | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-GOGO | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-GOGR | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-GOAQ | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-GRRE | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-GROR | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-GRGO | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-GRGR | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-GRAQ | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-AQRE | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-AQOR | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-AQGO | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-AQGR | 20 (40 μL) | 200 μL |
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| NFE2L1-NPEPPS-20-AQAQ | 20 (40 μL) | 200 μL |
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NFE2L1 Gene Summary
This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for "nuclear respiratory factor 1" which has an official symbol of NRF1. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Factor, Erythroid 2 Like 1
Chromosome: CHR17: 46125685 -46138907
Locus: 17q21.32
NPEPPS Gene Summary
This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008]
Gene Name: Aminopeptidase Puromycin Sensitive
Chromosome: CHR17: 45608443 -45700642
Locus: 17q21.32
Gene Diseases
The NFE2L1 NPEPPS Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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