NFAT5-CHST4 Fusion FISH Probe
The NFAT5-CHST4 Fusion FISH Probe is used to confirm a fusion of the NFAT5 and CHST4 genes. The fusion of the NFAT5 and CHST4 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NFAT5-CHST4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-RERE | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-REOR | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-REGO | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-REGR | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-REAQ | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-ORRE | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-OROR | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-ORGO | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-ORAQ | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-GORE | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-GOOR | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-GOGO | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-GOGR | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-GOAQ | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-GRRE | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-GROR | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-GRGO | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-GRGR | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-GRAQ | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-AQRE | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-AQOR | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-AQGO | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-AQGR | 20 (40 μL) | 200 μL |
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| NFAT5-CHST4-20-AQAQ | 20 (40 μL) | 200 μL |
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CHST4 Gene Summary
This gene encodes an N-acetylglucosamine 6-O sulfotransferase. The encoded enzyme transfers sulfate from 3'phosphoadenosine 5'phospho-sulfate to the 6-hydroxyl group of N-acetylglucosamine on glycoproteins. This protein is localized to the Golgi and is involved in the modification of glycan structures on ligands of the lymphocyte homing receptor L-selectin. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]
Gene Name: Carbohydrate Sulfotransferase 4
Chromosome: CHR16: 71560022 -71572493
Locus: 16q22.2
NFAT5 Gene Summary
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Factor Of Activated T-cells 5
Chromosome: CHR16: 69599868 -69738569
Locus: 16q22.1
Gene Diseases
The NFAT5 CHST4 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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