NF1-TRMT61B Fusion FISH Probe
The NF1-TRMT61B Fusion FISH Probe is used to confirm a fusion of the NF1 and TRMT61B genes. The fusion of the NF1 and TRMT61B genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NF1-TRMT61B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-RERE | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-REOR | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-REGO | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-REGR | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-REAQ | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-ORRE | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-OROR | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-ORGO | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-ORAQ | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-GORE | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-GOOR | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-GOGO | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-GOGR | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-GOAQ | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-GRRE | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-GROR | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-GRGO | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-GRGR | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-GRAQ | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-AQRE | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-AQOR | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-AQGO | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-AQGR | 20 (40 μL) | 200 μL |
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| NF1-TRMT61B-20-AQAQ | 20 (40 μL) | 200 μL |
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NF1 Gene Summary
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Neurofibromin 1
Chromosome: CHR17: 29421944 -29704695
Locus: 17q11.2
TRMT61B Gene Summary
The TRNA Methyltransferase 61B (TRMT61B) gene is located on chr2 :29072687-29093175 at 2p23.2.
Gene Name: TRNA Methyltransferase 61B
Chromosome: CHR2: 29072687 -29093175
Locus: 2p23.2
Gene Diseases
The NF1 TRMT61B Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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