NEXN-AK5 Fusion FISH Probe
The NEXN-AK5 Fusion FISH Probe is used to confirm a fusion of the NEXN and AK5 genes. The fusion of the NEXN and AK5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NEXN-AK5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-RERE | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-REOR | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-REGO | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-REGR | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-REAQ | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-ORRE | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-OROR | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-ORGO | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-ORAQ | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-GORE | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-GOOR | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-GOGO | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-GOGR | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-GOAQ | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-GRRE | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-GROR | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-GRGO | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-GRGR | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-GRAQ | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-AQRE | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-AQOR | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-AQGO | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-AQGR | 20 (40 μL) | 200 μL |
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| NEXN-AK5-20-AQAQ | 20 (40 μL) | 200 μL |
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AK5 Gene Summary
This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Adenylate Kinase 5
Chromosome: CHR1: 77747661 -78025654
Locus: 1p31.1
NEXN Gene Summary
This gene encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
Gene Name: Nexilin F-actin Binding Protein
Chromosome: CHR1: 78354199 -78409578
Locus: 1p31.1
Gene Diseases
The NEXN AK5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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