NEO1-NR2E3 Fusion FISH Probe
The NEO1-NR2E3 Fusion FISH Probe is used to confirm a fusion of the NEO1 and NR2E3 genes. The fusion of the NEO1 and NR2E3 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NEO1-NR2E3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-RERE | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-REOR | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-REGO | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-REGR | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-REAQ | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-ORRE | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-OROR | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-ORGO | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-ORAQ | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-GORE | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-GOOR | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-GOGO | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-GOGR | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-GOAQ | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-GRRE | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-GROR | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-GRGO | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-GRGR | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-GRAQ | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-AQRE | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-AQOR | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-AQGO | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-AQGR | 20 (40 μL) | 200 μL |
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| NEO1-NR2E3-20-AQAQ | 20 (40 μL) | 200 μL |
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NEO1 Gene Summary
This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Gene Name: Neogenin 1
Chromosome: CHR15: 73344824 -73597547
Locus: 15q24.1
NR2E3 Gene Summary
This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Receptor Subfamily 2 Group E Member 3
Chromosome: CHR15: 72102893 -72110597
Locus: 15q23
Gene Diseases
The NEO1 NR2E3 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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