NEK7-RAB3GAP2 Fusion FISH Probe
The NEK7-RAB3GAP2 Fusion FISH Probe is used to confirm a fusion of the NEK7 and RAB3GAP2 genes. The fusion of the NEK7 and RAB3GAP2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NEK7-RAB3GAP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-RERE | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-REOR | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-REGO | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-REGR | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-REAQ | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-ORRE | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-OROR | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-ORGO | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-GORE | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-GOOR | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-GOGO | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-GOGR | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-GRRE | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-GROR | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-GRGO | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-GRGR | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-AQRE | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-AQOR | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-AQGO | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-AQGR | 20 (40 μL) | 200 μL |
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| NEK7-RAB3GAP2-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB3GAP2 Gene Summary
The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009]
Gene Name: RAB3 GTPase Activating Non-catalytic Protein Subunit 2
Chromosome: CHR1: 220321609 -220445843
Locus: 1q41
NEK7 Gene Summary
NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.[supplied by OMIM, Jul 2002]
Gene Name: NIMA Related Kinase 7
Chromosome: CHR1: 198126107 -198291548
Locus: 1q31.3
Gene Diseases
The NEK7 RAB3GAP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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