NEK7-CD1C Fusion FISH Probe
The NEK7-CD1C Fusion FISH Probe is used to confirm a fusion of the NEK7 and CD1C genes. The fusion of the NEK7 and CD1C genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NEK7-CD1C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-RERE | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-REOR | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-REGO | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-REGR | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-REAQ | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-ORRE | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-OROR | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-ORGO | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-ORAQ | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-GORE | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-GOOR | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-GOGO | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-GOGR | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-GOAQ | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-GRRE | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-GROR | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-GRGO | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-GRGR | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-GRAQ | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-AQRE | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-AQOR | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-AQGO | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-AQGR | 20 (40 μL) | 200 μL |
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| NEK7-CD1C-20-AQAQ | 20 (40 μL) | 200 μL |
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CD1C Gene Summary
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
Gene Name: CD1c Molecule
Chromosome: CHR1: 158259562 -158264564
Locus: 1q23.1
NEK7 Gene Summary
NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.[supplied by OMIM, Jul 2002]
Gene Name: NIMA Related Kinase 7
Chromosome: CHR1: 198126107 -198291548
Locus: 1q31.3
Gene Diseases
The NEK7 CD1C Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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