NEK7-CADM3 Fusion FISH Probe
The NEK7-CADM3 Fusion FISH Probe is used to confirm a fusion of the NEK7 and CADM3 genes. The fusion of the NEK7 and CADM3 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NEK7-CADM3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-RERE | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-REOR | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-REGO | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-REGR | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-REAQ | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-ORRE | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-OROR | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-ORGO | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-ORAQ | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-GORE | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-GOOR | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-GOGO | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-GOGR | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-GOAQ | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-GRRE | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-GROR | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-GRGO | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-GRGR | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-GRAQ | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-AQRE | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-AQOR | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-AQGO | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-AQGR | 20 (40 μL) | 200 μL |
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| NEK7-CADM3-20-AQAQ | 20 (40 μL) | 200 μL |
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CADM3 Gene Summary
The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene. [provided by RefSeq, Oct 2016]
Gene Name: Cell Adhesion Molecule 3
Chromosome: CHR1: 159141376 -159172932
Locus: 1q23.2
NEK7 Gene Summary
NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.[supplied by OMIM, Jul 2002]
Gene Name: NIMA Related Kinase 7
Chromosome: CHR1: 198126107 -198291548
Locus: 1q31.3
Gene Diseases
The NEK7 CADM3 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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