NEIL2-TTC7B Fusion FISH Probe
The NEIL2-TTC7B Fusion FISH Probe is used to confirm a fusion of the NEIL2 and TTC7B genes. The fusion of the NEIL2 and TTC7B genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NEIL2-TTC7B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-RERE | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-REOR | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-REGO | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-REGR | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-REAQ | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-ORRE | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-OROR | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-ORGO | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-ORAQ | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-GORE | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-GOOR | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-GOGO | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-GOGR | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-GOAQ | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-GRRE | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-GROR | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-GRGO | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-GRGR | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-GRAQ | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-AQRE | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-AQOR | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-AQGO | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-AQGR | 20 (40 μL) | 200 μL |
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| NEIL2-TTC7B-20-AQAQ | 20 (40 μL) | 200 μL |
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TTC7B Gene Summary
The Tetratricopeptide Repeat Domain 7B (TTC7B) gene is located on chr14 :91006931-91282761 at 14q32.11.
Gene Name: Tetratricopeptide Repeat Domain 7B
Chromosome: CHR14: 91006931 -91282761
Locus: 14q32.11
NEIL2 Gene Summary
This gene encodes a member of the Fpg/Nei family of DNA glycosylases. These glycosylases initiate the first step in base excision repair by cleaving oxidatively damaged bases and introducing a DNA strand break via their abasic site lyase activity. This enzyme is primarily associated with DNA repair during transcription and acts prefentially on cytosine-derived lesions, particularly 5-hydroxyuracil and 5-hydroxycytosine. It contains an N-terminal catalytic domain, a hinge region, and a C-terminal DNA-binding domain with helix-two-turn-helix and zinc finger motifs. This enzyme interacts with the X-ray cross complementing factor 1 scaffold protein as part of a multi-protein DNA repair complex. A pseudogene of this gene has been identified. [provided by RefSeq, Mar 2017]
Gene Name: Nei Like DNA Glycosylase 2
Chromosome: CHR8: 11627171 -11644854
Locus: 8p23.1
Gene Diseases
The NEIL2 TTC7B Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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