NDUFS4-TMPRSS2 Fusion FISH Probe
The NDUFS4-TMPRSS2 Fusion FISH Probe is used to confirm a fusion of the NDUFS4 and TMPRSS2 genes. The fusion of the NDUFS4 and TMPRSS2 genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NDUFS4-TMPRSS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-RERE | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-REOR | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-REGO | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-REGR | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-REAQ | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-ORRE | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-OROR | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-ORGO | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-GORE | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-GOOR | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-GOGO | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-GOGR | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-GRRE | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-GROR | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-GRGO | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-GRGR | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-AQRE | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-AQOR | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-AQGO | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-AQGR | 20 (40 μL) | 200 μL |
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| NDUFS4-TMPRSS2-20-AQAQ | 20 (40 μL) | 200 μL |
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NDUFS4 Gene Summary
This gene encodes an nuclear-encoded accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I, or NADH:ubiquinone oxidoreductase). Complex I removes electrons from NADH and passes them to the electron acceptor ubiquinone. Mutations in this gene can cause mitochondrial complex I deficiencies such as Leigh syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: NADH:ubiquinone Oxidoreductase Subunit S4
Chromosome: CHR5: 52856464 -52979171
Locus: 5q11.2
TMPRSS2 Gene Summary
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Gene Name: Transmembrane Protease, Serine 2
Chromosome: CHR21: 42836477 -42880085
Locus: 21q22.3
Gene Diseases
The NDUFS4 TMPRSS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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