NDUFS4-EXTL3 Fusion FISH Probe
The NDUFS4-EXTL3 Fusion FISH Probe is used to confirm a fusion of the NDUFS4 and EXTL3 genes. The fusion of the NDUFS4 and EXTL3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NDUFS4-EXTL3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-RERE | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-REOR | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-REGO | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-REGR | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-REAQ | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-ORRE | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-OROR | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-ORGO | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-ORAQ | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-GORE | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-GOOR | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-GOGO | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-GOGR | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-GOAQ | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-GRRE | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-GROR | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-GRGO | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-GRGR | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-GRAQ | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-AQRE | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-AQOR | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-AQGO | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-AQGR | 20 (40 μL) | 200 μL |
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| NDUFS4-EXTL3-20-AQAQ | 20 (40 μL) | 200 μL |
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EXTL3 Gene Summary
This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012]
Gene Name: Exostosin Like Glycosyltransferase 3
Chromosome: CHR8: 28559152 -28611202
Locus: 8p21.1
NDUFS4 Gene Summary
This gene encodes an nuclear-encoded accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I, or NADH:ubiquinone oxidoreductase). Complex I removes electrons from NADH and passes them to the electron acceptor ubiquinone. Mutations in this gene can cause mitochondrial complex I deficiencies such as Leigh syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: NADH:ubiquinone Oxidoreductase Subunit S4
Chromosome: CHR5: 52856464 -52979171
Locus: 5q11.2
Gene Diseases
The NDUFS4 EXTL3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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