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NDUFS2-SLC24A2 Fusion FISH Probe

The NDUFS2-SLC24A2 Fusion FISH Probe is used to confirm a fusion of the NDUFS2 and SLC24A2 genes. The fusion of the NDUFS2 and SLC24A2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NDUFS2-SLC24A2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-RERE 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-REOR 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-REGO 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-REGR 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-REAQ 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-ORRE 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-OROR 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-ORGO 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-ORAQ 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-GORE 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-GOOR 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-GOGO 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-GOGR 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-GOAQ 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-GRRE 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-GROR 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-GRGO 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-GRGR 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-GRAQ 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-AQRE 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-AQOR 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-AQGO 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-AQGR 20 (40 μL) 200 μL
NDUFS2-SLC24A2-20-AQAQ 20 (40 μL) 200 μL

NDUFS2 Gene Summary

The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

Gene Name: NADH:ubiquinone Oxidoreductase Core Subunit S2

Chromosome: CHR1: 161169104 -161184184

Locus: 1q23.3

SLC24A2 Gene Summary

This gene encodes a member of the calcium/cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone/brain exchanger that can mediate a light-induced decrease in free Ca2+ concentration. This protein may also play a neuroprotective role during ischemic brain injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Gene Name: Solute Carrier Family 24 Member 2

Chromosome: CHR9: 19507449 -19787017

Locus: 9p22.1-p21.3

Gene Diseases

The NDUFS2 SLC24A2 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.