NDUFA7-PRKCG Fusion FISH Probe
The NDUFA7-PRKCG Fusion FISH Probe is used to confirm a fusion of the NDUFA7 and PRKCG genes. The fusion of the NDUFA7 and PRKCG genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NDUFA7-PRKCG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-RERE | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-REOR | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-REGO | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-REGR | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-REAQ | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-ORRE | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-OROR | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-ORGO | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-ORAQ | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-GORE | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-GOOR | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-GOGO | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-GOGR | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-GOAQ | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-GRRE | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-GROR | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-GRGO | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-GRGR | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-GRAQ | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-AQRE | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-AQOR | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-AQGO | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-AQGR | 20 (40 μL) | 200 μL |
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| NDUFA7-PRKCG-20-AQAQ | 20 (40 μL) | 200 μL |
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NDUFA7 Gene Summary
This gene encodes a subunit of NADH:ubiquinone oxidoreductase (complex I), which is a multiprotein complex located in the inner mitochondrial membrane. Complex I functions in the transfer of electrons from NADH to the respiratory chain. [provided by RefSeq, Mar 2011]
Gene Name: NADH:ubiquinone Oxidoreductase Subunit A7
Chromosome: CHR19: 8376183 -8386280
Locus: 19p13.2
PRKCG Gene Summary
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Name: Protein Kinase C Gamma
Chromosome: CHR19: 54385466 -54410901
Locus: 19q13.42
Gene Diseases
The NDUFA7 PRKCG Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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