NDUFA10-SGPP2 Fusion FISH Probe
The NDUFA10-SGPP2 Fusion FISH Probe is used to confirm a fusion of the NDUFA10 and SGPP2 genes. The fusion of the NDUFA10 and SGPP2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NDUFA10-SGPP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-RERE | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-REOR | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-REGO | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-REGR | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-REAQ | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-ORRE | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-OROR | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-ORGO | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-GORE | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-GOOR | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-GOGO | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-GOGR | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-GRRE | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-GROR | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-GRGO | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-GRGR | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-AQRE | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-AQOR | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-AQGO | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-AQGR | 20 (40 μL) | 200 μL |
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| NDUFA10-SGPP2-20-AQAQ | 20 (40 μL) | 200 μL |
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NDUFA10 Gene Summary
The protein encoded by this gene is a component of 42 kDa complex I, the first enzyme complex in the electron transport chain of mitochondria. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. A mutation in this gene was found in an individual with Leigh syndrome. [provided by RefSeq, Apr 2016]
Gene Name: NADH:ubiquinone Oxidoreductase Subunit A10
Chromosome: CHR2: 240896788 -240964819
Locus: 2q37.3
SGPP2 Gene Summary
The protein encoded by this gene is a transmembrane protein that degrades the bioactive signaling molecule sphingosine 1-phosphate. The encoded protein is induced during inflammatory responses and has been shown to be downregulated by the microRNA-31 tumor suppressor. Alternative splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]
Gene Name: Sphingosine-1-phosphate Phosphatase 2
Chromosome: CHR2: 223289321 -223423617
Locus: 2q36.1
Gene Diseases
The NDUFA10 SGPP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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