NDUFA10-ANXA4 Fusion FISH Probe
The NDUFA10-ANXA4 Fusion FISH Probe is used to confirm a fusion of the NDUFA10 and ANXA4 genes. The fusion of the NDUFA10 and ANXA4 genes has been associated with Skin Cutaneous Melanoma, and Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NDUFA10-ANXA4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-RERE | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-REOR | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-REGO | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-REGR | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-REAQ | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-ORRE | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-OROR | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-ORGO | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-ORAQ | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-GORE | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-GOOR | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-GOGO | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-GOGR | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-GOAQ | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-GRRE | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-GROR | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-GRGO | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-GRGR | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-GRAQ | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-AQRE | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-AQOR | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-AQGO | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-AQGR | 20 (40 μL) | 200 μL |
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| NDUFA10-ANXA4-20-AQAQ | 20 (40 μL) | 200 μL |
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ANXA4 Gene Summary
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]
Gene Name: Annexin A4
Chromosome: CHR2: 69969126 -70053596
Locus: 2p13.3
NDUFA10 Gene Summary
The protein encoded by this gene is a component of 42 kDa complex I, the first enzyme complex in the electron transport chain of mitochondria. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. A mutation in this gene was found in an individual with Leigh syndrome. [provided by RefSeq, Apr 2016]
Gene Name: NADH:ubiquinone Oxidoreductase Subunit A10
Chromosome: CHR2: 240896788 -240964819
Locus: 2q37.3
Gene Diseases
The NDUFA10 ANXA4 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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