NDRG1-ST3GAL1 Fusion FISH Probe
The NDRG1-ST3GAL1 Fusion FISH Probe is used to confirm a fusion of the NDRG1 and ST3GAL1 genes. The fusion of the NDRG1 and ST3GAL1 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NDRG1-ST3GAL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-RERE | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-REOR | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-REGO | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-REGR | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-REAQ | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-ORRE | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-OROR | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-ORGO | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-GORE | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-GOOR | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-GOGO | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-GOGR | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-GRRE | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-GROR | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-GRGO | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-GRGR | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-AQRE | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-AQOR | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-AQGO | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-AQGR | 20 (40 μL) | 200 μL |
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| NDRG1-ST3GAL1-20-AQAQ | 20 (40 μL) | 200 μL |
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ST3GAL1 Gene Summary
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]
Gene Name: ST3 Beta-galactoside Alpha-2,3-sialyltransferase 1
Chromosome: CHR8: 134467090 -134584183
Locus: 8q24.22
NDRG1 Gene Summary
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Gene Name: N-myc Downstream Regulated 1
Chromosome: CHR8: 134249413 -134309547
Locus: 8q24.22
Gene Diseases
The NDRG1 ST3GAL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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