NCL-SQSTM1 Fusion FISH Probe
The NCL-SQSTM1 Fusion FISH Probe is used to confirm a fusion of the NCL and SQSTM1 genes. The fusion of the NCL and SQSTM1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCL-SQSTM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-RERE | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-REOR | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-REGO | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-REGR | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-REAQ | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-ORRE | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-OROR | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-ORGO | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-GORE | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-GOOR | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-GOGO | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-GOGR | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-GRRE | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-GROR | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-GRGO | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-GRGR | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-AQRE | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-AQOR | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-AQGO | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-AQGR | 20 (40 μL) | 200 μL |
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| NCL-SQSTM1-20-AQAQ | 20 (40 μL) | 200 μL |
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NCL Gene Summary
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20. [provided by RefSeq, Jul 2008]
Gene Name: Nucleolin
Chromosome: CHR2: 232319458 -232329205
Locus: 2q37.1
SQSTM1 Gene Summary
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]
Gene Name: Sequestosome 1
Chromosome: CHR5: 179233387 -179265077
Locus: 5q35.3
Gene Diseases
The NCL SQSTM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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