NCKAP5-NMI Fusion FISH Probe
The NCKAP5-NMI Fusion FISH Probe is used to confirm a fusion of the NCKAP5 and NMI genes. The fusion of the NCKAP5 and NMI genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCKAP5-NMI-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-RERE | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-REOR | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-REGO | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-REGR | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-REAQ | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-ORRE | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-OROR | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-ORGO | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-GORE | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-GOOR | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-GOGO | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-GOGR | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-GRRE | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-GROR | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-GRGO | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-GRGR | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-AQRE | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-AQOR | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-AQGO | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-AQGR | 20 (40 μL) | 200 μL |
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| NCKAP5-NMI-20-AQAQ | 20 (40 μL) | 200 μL |
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NMI Gene Summary
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008]
Gene Name: N-myc And STAT Interactor
Chromosome: CHR2: 152126981 -152146430
Locus: 2q23.3
NCKAP5 Gene Summary
The NCK Associated Protein 5 (NCKAP5) gene is located on chr2 :133429371-134326031 at 2q21.2.
Gene Name: NCK Associated Protein 5
Chromosome: CHR2: 133429371 -134326031
Locus: 2q21.2
Gene Diseases
The NCKAP5 NMI Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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