NCK2-NUP93 Fusion FISH Probe
The NCK2-NUP93 Fusion FISH Probe is used to confirm a fusion of the NCK2 and NUP93 genes. The fusion of the NCK2 and NUP93 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCK2-NUP93-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-RERE | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-REOR | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-REGO | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-REGR | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-REAQ | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-ORRE | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-OROR | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-ORGO | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-GORE | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-GOOR | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-GOGO | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-GOGR | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-GRRE | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-GROR | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-GRGO | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-GRGR | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-AQRE | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-AQOR | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-AQGO | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-AQGR | 20 (40 μL) | 200 μL |
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| NCK2-NUP93-20-AQAQ | 20 (40 μL) | 200 μL |
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NCK2 Gene Summary
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: NCK Adaptor Protein 2
Chromosome: CHR2: 106361519 -106510730
Locus: 2q12.2
NUP93 Gene Summary
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene encodes a nucleoporin protein that localizes both to the basket of the pore and to the nuclear entry of the central gated channel of the pore. The encoded protein is a target of caspase cysteine proteases that play a central role in programmed cell death by apoptosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Gene Name: Nucleoporin 93
Chromosome: CHR16: 56764016 -56878861
Locus: 16q13
Gene Diseases
The NCK2 NUP93 Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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