NCK2-MRPS9 Fusion FISH Probe
The NCK2-MRPS9 Fusion FISH Probe is used to confirm a fusion of the NCK2 and MRPS9 genes. The fusion of the NCK2 and MRPS9 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCK2-MRPS9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-RERE | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-REOR | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-REGO | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-REGR | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-REAQ | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-ORRE | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-OROR | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-ORGO | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-GORE | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-GOOR | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-GOGO | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-GOGR | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-GRRE | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-GROR | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-GRGO | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-GRGR | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-AQRE | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-AQOR | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-AQGO | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-AQGR | 20 (40 μL) | 200 μL |
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| NCK2-MRPS9-20-AQAQ | 20 (40 μL) | 200 μL |
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NCK2 Gene Summary
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: NCK Adaptor Protein 2
Chromosome: CHR2: 106361519 -106510730
Locus: 2q12.2
MRPS9 Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. [provided by RefSeq, Jul 2008]
Gene Name: Mitochondrial Ribosomal Protein S9
Chromosome: CHR2: 105654482 -105716418
Locus: 2q12.1
Gene Diseases
The NCK2 MRPS9 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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