NCAPH-KCNIP3 Fusion FISH Probe
The NCAPH-KCNIP3 Fusion FISH Probe is used to confirm a fusion of the NCAPH and KCNIP3 genes. The fusion of the NCAPH and KCNIP3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCAPH-KCNIP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-RERE | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-REOR | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-REGO | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-REGR | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-REAQ | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-ORRE | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-OROR | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-ORGO | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-GORE | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-GOOR | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-GOGO | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-GOGR | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-GRRE | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-GROR | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-GRGO | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-GRGR | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-AQRE | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-AQOR | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-AQGO | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-AQGR | 20 (40 μL) | 200 μL |
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| NCAPH-KCNIP3-20-AQAQ | 20 (40 μL) | 200 μL |
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NCAPH Gene Summary
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013]
Gene Name: Non-SMC Condensin I Complex Subunit H
Chromosome: CHR2: 97001483 -97041274
Locus: 2q11.2
KCNIP3 Gene Summary
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Voltage-gated Channel Interacting Protein 3
Chromosome: CHR2: 95963071 -96051825
Locus: 2q11.1
Gene Diseases
The NCAPH KCNIP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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