NBEA-POSTN Fusion FISH Probe
The NBEA-POSTN Fusion FISH Probe is used to confirm a fusion of the NBEA and POSTN genes. The fusion of the NBEA and POSTN genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NBEA-POSTN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-RERE | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-REOR | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-REGO | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-REGR | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-REAQ | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-ORRE | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-OROR | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-ORGO | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-ORAQ | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-GORE | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-GOOR | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-GOGO | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-GOGR | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-GOAQ | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-GRRE | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-GROR | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-GRGO | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-GRGR | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-GRAQ | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-AQRE | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-AQOR | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-AQGO | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-AQGR | 20 (40 μL) | 200 μL |
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| NBEA-POSTN-20-AQAQ | 20 (40 μL) | 200 μL |
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POSTN Gene Summary
This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Gene Name: Periostin
Chromosome: CHR13: 38136718 -38172981
Locus: 13q13.3
NBEA Gene Summary
This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011]
Gene Name: Neurobeachin
Chromosome: CHR13: 35516423 -36246873
Locus: 13q13.3
Gene Diseases
The NBEA POSTN Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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