NBAS-SPIRE1 Fusion FISH Probe
The NBAS-SPIRE1 Fusion FISH Probe is used to confirm a fusion of the NBAS and SPIRE1 genes. The fusion of the NBAS and SPIRE1 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NBAS-SPIRE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-RERE | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-REOR | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-REGO | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-REGR | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-REAQ | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-ORRE | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-OROR | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-ORGO | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-GORE | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-GOOR | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-GOGO | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-GOGR | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-GRRE | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-GROR | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-GRGO | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-GRGR | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-AQRE | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-AQOR | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-AQGO | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-AQGR | 20 (40 μL) | 200 μL |
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| NBAS-SPIRE1-20-AQAQ | 20 (40 μL) | 200 μL |
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NBAS Gene Summary
This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. [provided by RefSeq, Oct 2012]
Gene Name: Neuroblastoma Amplified Sequence
Chromosome: CHR2: 15307031 -15701454
Locus: 2p24.3
SPIRE1 Gene Summary
Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]).[supplied by OMIM, Mar 2008]
Gene Name: Spire Type Actin Nucleation Factor 1
Chromosome: CHR18: 12446510 -12657912
Locus: 18p11.21
Gene Diseases
The NBAS SPIRE1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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