NBAS-DDX1 Fusion FISH Probe
The NBAS-DDX1 Fusion FISH Probe is used to confirm a fusion of the NBAS and DDX1 genes. The fusion of the NBAS and DDX1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NBAS-DDX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-RERE | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-REOR | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-REGO | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-REGR | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-REAQ | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-ORRE | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-OROR | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-ORGO | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-GORE | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-GOOR | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-GOGO | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-GOGR | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-GRRE | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-GROR | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-GRGO | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-GRGR | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-AQRE | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-AQOR | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-AQGO | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-AQGR | 20 (40 μL) | 200 μL |
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| NBAS-DDX1-20-AQAQ | 20 (40 μL) | 200 μL |
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DDX1 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin. [provided by RefSeq, Jul 2008]
Gene Name: DEAD-box Helicase 1
Chromosome: CHR2: 15731769 -15771225
Locus: 2p24.3
NBAS Gene Summary
This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. [provided by RefSeq, Oct 2012]
Gene Name: Neuroblastoma Amplified Sequence
Chromosome: CHR2: 15307031 -15701454
Locus: 2p24.3
Gene Diseases
The NBAS DDX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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