NASP-PIK3R3 Fusion FISH Probe
The NASP-PIK3R3 Fusion FISH Probe is used to confirm a fusion of the NASP and PIK3R3 genes. The fusion of the NASP and PIK3R3 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NASP-PIK3R3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-RERE | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-REOR | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-REGO | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-REGR | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-REAQ | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-ORRE | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-OROR | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-ORGO | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-ORAQ | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-GORE | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-GOOR | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-GOGO | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-GOGR | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-GOAQ | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-GRRE | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-GROR | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-GRGO | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-GRGR | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-GRAQ | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-AQRE | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-AQOR | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-AQGO | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-AQGR | 20 (40 μL) | 200 μL |
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| NASP-PIK3R3-20-AQAQ | 20 (40 μL) | 200 μL |
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NASP Gene Summary
This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Autoantigenic Sperm Protein
Chromosome: CHR1: 46049659 -46084578
Locus: 1p34.1
PIK3R3 Gene Summary
Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016]
Gene Name: Phosphoinositide-3-kinase Regulatory Subunit 3
Chromosome: CHR1: 46505811 -46598708
Locus: 1p34.1
Gene Diseases
The NASP PIK3R3 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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