NAPSA-SEC63 Fusion FISH Probe
The NAPSA-SEC63 Fusion FISH Probe is used to confirm a fusion of the NAPSA and SEC63 genes. The fusion of the NAPSA and SEC63 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NAPSA-SEC63-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-RERE | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-REOR | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-REGR | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-OROR | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-GROR | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| NAPSA-SEC63-20-AQAQ | 20 (40 μL) | 200 μL |
|
NAPSA Gene Summary
This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]
Gene Name: Napsin A Aspartic Peptidase
Chromosome: CHR19: 50861733 -50868931
Locus: 19q13.33
SEC63 Gene Summary
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Gene Name: SEC63 Homolog, Protein Translocation Regulator
Chromosome: CHR6: 108188959 -108279482
Locus: 6q21
Gene Diseases
The NAPSA SEC63 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|