NAPSA-DDX27 Fusion FISH Probe
The NAPSA-DDX27 Fusion FISH Probe is used to confirm a fusion of the NAPSA and DDX27 genes. The fusion of the NAPSA and DDX27 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NAPSA-DDX27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-RERE | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-REOR | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-REGO | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-REGR | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-REAQ | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-ORRE | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-OROR | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-ORGO | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-ORAQ | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-GORE | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-GOOR | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-GOGO | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-GOGR | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-GOAQ | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-GRRE | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-GROR | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-GRGO | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-GRGR | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-GRAQ | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-AQRE | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-AQOR | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-AQGO | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-AQGR | 20 (40 μL) | 200 μL |
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| NAPSA-DDX27-20-AQAQ | 20 (40 μL) | 200 μL |
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NAPSA Gene Summary
This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]
Gene Name: Napsin A Aspartic Peptidase
Chromosome: CHR19: 50861733 -50868931
Locus: 19q13.33
DDX27 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]
Gene Name: DEAD-box Helicase 27
Chromosome: CHR20: 47835831 -47860614
Locus: 20q13.13
Gene Diseases
The NAPSA DDX27 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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