NADK-GNB1 Fusion FISH Probe
The NADK-GNB1 Fusion FISH Probe is used to confirm a fusion of the NADK and GNB1 genes. The fusion of the NADK and GNB1 genes has been associated with Head And Neck Squamous Cell Carcinoma , and Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NADK-GNB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-RERE | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-REOR | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-REGO | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-REGR | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-REAQ | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-ORRE | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-OROR | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-ORGO | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-GORE | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-GOOR | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-GOGO | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-GOGR | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-GRRE | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-GROR | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-GRGO | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-GRGR | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-AQRE | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-AQOR | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-AQGO | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-AQGR | 20 (40 μL) | 200 μL |
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| NADK-GNB1-20-AQAQ | 20 (40 μL) | 200 μL |
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GNB1 Gene Summary
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: G Protein Subunit Beta 1
Chromosome: CHR1: 1716724 -1822526
Locus: 1p36.33
NADK Gene Summary
NADK catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions (Lerner et al., 2001 [PubMed 11594753]).[supplied by OMIM, Mar 2008]
Gene Name: NAD Kinase
Chromosome: CHR1: 1682670 -1711508
Locus: 1p36.33
Gene Diseases
The NADK GNB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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