N4BP1-DDX19B Fusion FISH Probe
The N4BP1-DDX19B Fusion FISH Probe is used to confirm a fusion of the N4BP1 and DDX19B genes. The fusion of the N4BP1 and DDX19B genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| N4BP1-DDX19B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-RERE | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-REOR | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-REGO | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-REGR | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-REAQ | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-ORRE | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-OROR | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-ORGO | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-ORAQ | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-GORE | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-GOOR | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-GOGO | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-GOGR | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-GOAQ | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-GRRE | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-GROR | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-GRGO | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-GRGR | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-GRAQ | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-AQRE | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-AQOR | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-AQGO | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-AQGR | 20 (40 μL) | 200 μL |
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| N4BP1-DDX19B-20-AQAQ | 20 (40 μL) | 200 μL |
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N4BP1 Gene Summary
The NEDD4 Binding Protein 1 (N4BP1) gene is located on chr16 :48572636-48644120 at 16q12.1.
Gene Name: NEDD4 Binding Protein 1
Chromosome: CHR16: 48572636 -48644120
Locus: 16q12.1
DDX19B Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: DEAD-box Helicase 19B
Chromosome: CHR16: 70333071 -70367731
Locus: 16q22.1
Gene Diseases
The N4BP1 DDX19B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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