MYSM1-ATG4C Fusion FISH Probe
The MYSM1-ATG4C Fusion FISH Probe is used to confirm a fusion of the MYSM1 and ATG4C genes. The fusion of the MYSM1 and ATG4C genes has been associated with Testicular Germ Cell Tumors. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYSM1-ATG4C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-RERE | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-REOR | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-REGO | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-REGR | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-REAQ | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-ORRE | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-OROR | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-ORGO | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-GORE | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-GOOR | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-GOGO | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-GOGR | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-GRRE | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-GROR | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-GRGO | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-GRGR | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-AQRE | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-AQOR | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-AQGO | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-AQGR | 20 (40 μL) | 200 μL |
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| MYSM1-ATG4C-20-AQAQ | 20 (40 μL) | 200 μL |
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ATG4C Gene Summary
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Autophagy Related 4C Cysteine Peptidase
Chromosome: CHR1: 63249776 -63330941
Locus: 1p31.3
MYSM1 Gene Summary
The Myb Like, SWIRM And MPN Domains 1 (MYSM1) gene is located on chr1 :59120410-59165747 at 1p32.1.
Gene Name: Myb Like, SWIRM And MPN Domains 1
Chromosome: CHR1: 59120410 -59165747
Locus: 1p32.1
Gene Diseases
The MYSM1 ATG4C Fusion has been associated with the following diseases:
| Disease Name |
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| Testicular Germ Cell Tumors |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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