MYPN-PLXDC2 Fusion FISH Probe
The MYPN-PLXDC2 Fusion FISH Probe is used to confirm a fusion of the MYPN and PLXDC2 genes. The fusion of the MYPN and PLXDC2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYPN-PLXDC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-RERE | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-REOR | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-REGO | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-REGR | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-REAQ | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-ORRE | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-OROR | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-ORGO | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-GORE | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-GOOR | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-GOGO | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-GOGR | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-GRRE | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-GROR | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-GRGO | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-GRGR | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-AQRE | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-AQOR | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-AQGO | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-AQGR | 20 (40 μL) | 200 μL |
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| MYPN-PLXDC2-20-AQAQ | 20 (40 μL) | 200 μL |
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MYPN Gene Summary
Striated muscle in vertebrates comprises large proteins which must be organized properly to contract efficiently. Z-lines in striated muscle are a sign of this organization, representing the ends of actin thin filaments, titin, nebulin or nebulette and accessory proteins required for structure and function. This gene encodes a protein which interacts with nebulin in skeletal muscle or nebulette in cardiac muscle and alpha-actinin. In addition, this gene product can interact with a protein with the I-band indicating it has a regulatory as well as structural function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Gene Name: Myopalladin
Chromosome: CHR10: 69869249 -69971773
Locus: 10q21.3
PLXDC2 Gene Summary
The Plexin Domain Containing 2 (PLXDC2) gene is located on chr10 :20105371-20569115 at 10p12.31.
Gene Name: Plexin Domain Containing 2
Chromosome: CHR10: 20105371 -20569115
Locus: 10p12.31
Gene Diseases
The MYPN PLXDC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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