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MYO9B-PNN Fusion FISH Probe

The MYO9B-PNN Fusion FISH Probe is used to confirm a fusion of the MYO9B and PNN genes. The fusion of the MYO9B and PNN genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MYO9B-PNN-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MYO9B-PNN-20-RERE 20 (40 μL) 200 μL
MYO9B-PNN-20-REOR 20 (40 μL) 200 μL
MYO9B-PNN-20-REGO 20 (40 μL) 200 μL
MYO9B-PNN-20-REGR 20 (40 μL) 200 μL
MYO9B-PNN-20-REAQ 20 (40 μL) 200 μL
MYO9B-PNN-20-ORRE 20 (40 μL) 200 μL
MYO9B-PNN-20-OROR 20 (40 μL) 200 μL
MYO9B-PNN-20-ORGO 20 (40 μL) 200 μL
MYO9B-PNN-20-ORAQ 20 (40 μL) 200 μL
MYO9B-PNN-20-GORE 20 (40 μL) 200 μL
MYO9B-PNN-20-GOOR 20 (40 μL) 200 μL
MYO9B-PNN-20-GOGO 20 (40 μL) 200 μL
MYO9B-PNN-20-GOGR 20 (40 μL) 200 μL
MYO9B-PNN-20-GOAQ 20 (40 μL) 200 μL
MYO9B-PNN-20-GRRE 20 (40 μL) 200 μL
MYO9B-PNN-20-GROR 20 (40 μL) 200 μL
MYO9B-PNN-20-GRGO 20 (40 μL) 200 μL
MYO9B-PNN-20-GRGR 20 (40 μL) 200 μL
MYO9B-PNN-20-GRAQ 20 (40 μL) 200 μL
MYO9B-PNN-20-AQRE 20 (40 μL) 200 μL
MYO9B-PNN-20-AQOR 20 (40 μL) 200 μL
MYO9B-PNN-20-AQGO 20 (40 μL) 200 μL
MYO9B-PNN-20-AQGR 20 (40 μL) 200 μL
MYO9B-PNN-20-AQAQ 20 (40 μL) 200 μL

MYO9B Gene Summary

This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Gene Name: Myosin IXB

Chromosome: CHR19: 17186590 -17324104

Locus: 19p13.11

PNN Gene Summary

The Pinin, Desmosome Associated Protein (PNN) gene is located on chr14 :39644386-39652422 at 14q21.1.

Gene Name: Pinin, Desmosome Associated Protein

Chromosome: CHR14: 39644386 -39652422

Locus: 14q21.1

Gene Diseases

The MYO9B PNN Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.