MYO9B-PNN Fusion FISH Probe
The MYO9B-PNN Fusion FISH Probe is used to confirm a fusion of the MYO9B and PNN genes. The fusion of the MYO9B and PNN genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO9B-PNN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-RERE | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-REOR | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-REGO | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-REGR | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-OROR | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-GORE | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-GROR | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO9B-PNN-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO9B Gene Summary
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin IXB
Chromosome: CHR19: 17186590 -17324104
Locus: 19p13.11
PNN Gene Summary
The Pinin, Desmosome Associated Protein (PNN) gene is located on chr14 :39644386-39652422 at 14q21.1.
Gene Name: Pinin, Desmosome Associated Protein
Chromosome: CHR14: 39644386 -39652422
Locus: 14q21.1
Gene Diseases
The MYO9B PNN Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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