MYO9A-GRB2 Fusion FISH Probe
The MYO9A-GRB2 Fusion FISH Probe is used to confirm a fusion of the MYO9A and GRB2 genes. The fusion of the MYO9A and GRB2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO9A-GRB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-RERE | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-REOR | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-REGO | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-REGR | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-OROR | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-GORE | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-GROR | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO9A-GRB2-20-AQAQ | 20 (40 μL) | 200 μL |
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GRB2 Gene Summary
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Growth Factor Receptor Bound Protein 2
Chromosome: CHR17: 73314156 -73401790
Locus: 17q25.1
MYO9A Gene Summary
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with Bardet-Biedl Syndrome. [provided by RefSeq, Dec 2011]
Gene Name: Myosin IXA
Chromosome: CHR15: 72118360 -72410422
Locus: 15q23
Gene Diseases
The MYO9A GRB2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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