MYO6-CRYL1 Fusion FISH Probe
The MYO6-CRYL1 Fusion FISH Probe is used to confirm a fusion of the MYO6 and CRYL1 genes. The fusion of the MYO6 and CRYL1 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO6-CRYL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-RERE | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-REOR | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-REGO | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-REGR | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-OROR | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-GORE | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-GROR | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO6-CRYL1-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO6 Gene Summary
This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Gene Name: Myosin VI
Chromosome: CHR6: 76458908 -76629254
Locus: 6q14.1
CRYL1 Gene Summary
The uronate cycle functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. The product of this gene catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate in the uronate cycle. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate. A similar gene in the rabbit is thought to serve a structural role in the lens of the eye. [provided by RefSeq, Jul 2008]
Gene Name: Crystallin Lambda 1
Chromosome: CHR13: 20977805 -21100012
Locus: 13q12.11
Gene Diseases
The MYO6 CRYL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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