MYO5B-COX6C Fusion FISH Probe
The MYO5B-COX6C Fusion FISH Probe is used to confirm a fusion of the MYO5B and COX6C genes. The fusion of the MYO5B and COX6C genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO5B-COX6C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-RERE | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-REOR | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-REGO | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-REGR | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-OROR | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-GORE | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-GROR | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO5B-COX6C-20-AQAQ | 20 (40 μL) | 200 μL |
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COX6C Gene Summary
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010]
Gene Name: Cytochrome C Oxidase Subunit 6C
Chromosome: CHR8: 100890222 -100906242
Locus: 8q22.2
MYO5B Gene Summary
The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. [provided by RefSeq, Sep 2009]
Gene Name: Myosin VB
Chromosome: CHR18: 47349155 -47721451
Locus: 18q21.1
Gene Diseases
The MYO5B COX6C Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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