MYO1E-TMCO3 Fusion FISH Probe
The MYO1E-TMCO3 Fusion FISH Probe is used to confirm a fusion of the MYO1E and TMCO3 genes. The fusion of the MYO1E and TMCO3 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MYO1E-TMCO3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MYO1E-TMCO3-20-AQAQ | 20 (40 μL) | 200 μL |
|
MYO1E Gene Summary
This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17. [provided by RefSeq, Jan 2012]
Gene Name: Myosin IE
Chromosome: CHR15: 59428562 -59665071
Locus: 15q22.2
TMCO3 Gene Summary
This gene encodes a member of the monovalent cation:proton antiporter 2 (CPA2) family of transporter proteins. Members of this family typically couple the export of monovalent cations, such as potassium or sodium, to the import of protons across cellular membranes. Mutations in this gene have been identified in patients with a rare inherited vision defect, cornea guttata with anterior polar cataract. [provided by RefSeq, Mar 2017]
Gene Name: Transmembrane And Coiled-coil Domains 3
Chromosome: CHR13: 114145307 -114204544
Locus: 13q34
Gene Diseases
The MYO1E TMCO3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|